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The
dsRNA segments and proteins of Colorado tick fever virus (CTFV) (genus Coltivirus,
family Reoviridae)
Recent
structural analyses [ ], references [in square brackets] last updated
21/05/2001 Available
as a word file
Genome
Segment†
Size
(bp) |
ORFs
bp |
Proteins
( ':
Function) |
Protein
Size aa
(Da) |
Protein
Location |
Copy
Number/
Particle |
Accession
Numbers |
Functions
and Properties |
1
(4350*) |
14-4321 |
VP1(Pol) |
(16304) |
- |
- |
NC_004181
|
RNA-dependent
RNA polymerase
[Orthoreovirus
lambda 3(Pol), Orbivirus VP 1(Pol), Rotavirus VP1(Pol) , Cypovirus
VP1 (Pol)] |
2
(3909*) |
46-3675 |
VP2 |
(136985) |
- |
- |
NC_004182 |
Methyltransferase,
cell-receptor recognition site |
3
(3586*) |
12-3560 |
VP3 |
(135015) |
- |
- |
NC_004183 |
RNA
replication factors |
4
(3157*) |
22-3105 |
VP4 |
(112411) |
- |
- |
NC_004184 |
- |
5
(2433*) |
78-2333 |
VP5
(CaP) |
(83793) |
- |
- |
NC_004185 |
Guanylyltransferase |
6
(2141*) |
15-2108 |
VP6 |
(77616) |
- |
- |
NC_004186 |
Nucleotide
binding, NTPase |
7
(2131*) |
24-2078 |
VP7 |
(76238) |
- |
- |
NC_004187 |
RNA
replication factors |
8
(2029) |
20-2002 |
VP8 |
(73947) |
- |
- |
NC_004188 |
- |
9
(1884*) |
41-1054
41-1849 |
VP9
(Hel) |
(38
)
(6734) |
- |
- |
NC_004180 |
Kinase,
helicase |
10
(1880*) |
12-1829 |
VP10 |
(6891) |
- |
- |
NC_004189 |
- |
11
(998*) |
40-789 |
VP11 |
(285) |
- |
- |
NC_004191 |
- |
12
(675*) |
20-577 |
VP12 |
(204) |
- |
- |
NC_004190 |
RNA
replication factors |
':
To facilitate comparisons of proteins across species, genera and families of
dsRNA viruses, protein structure / function indicators can be / have been added
to protein names: (Pol) = RNA polymerase; (CaP) = capping enzyme
(guanylyltransferase); (Hel) = helicase enzyme.
Other
species within the genus may have cognate proteins with significant differences
in sizes. ‡ Proteins with similar functions from other
genera.
Constructed
by Peter Mertens with data provided by provided by Houssam Attoui
Reference
List
1. Attoui
H, Charrel R, Billoir F, Cantaloube JF, De Micco P, de Lamballerie X (1998)
Comparative sequence analysis of American, European and Asian isolates of
viruses in the genus Coltivirus. J. Gen. Virol. 79: 2481-2489.
2.
Attoui, H., F. Billoir, J. F. Cantaloube, P. Biagini, P. De Micco, and X. de
Lamballerie. 2000. Sequence determination and analysis of the full-length genome
of Colorado tick fever virus, the type species of genus Coltivirus (family
Reoviridae). Biochem. Biophys.Res.Com. 273: 1121-1125.
3. Attoui,
H., F. Mohd Jaafar, P. Biagini, J. F. Cantaloube, P. de Micco, F. A. Murphy, and
X. de Lamballerie. 2002. Genus Coltivirus (Family Reoviridae): Genomic and
Morphologic Characterization of Old World and New World Viruses. Arch. Virol.
147: 533-561.
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